8VF2

CryoEM structure of Ku homodimer super-complex with linear DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, I (I, G)	DNA (40-MER)	polymer	40	12239.8	2		synthetic construct
2	B, J (J, H)	DNA (40-MER)	polymer	40	12392.0	2		synthetic construct
3	C, D, E, F, G... (A, B, C, D, E...)	Non-homologous end joining protein Ku	polymer	295	33609.9	6	UniProt (P9WKD9) Pfam (PF02735)	Mycobacterium tuberculosis H37Rv	Mt-Ku

Sequence modifications

A, B, C, D, E, F: 1 - 273 (UniProt: P9WKD9)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
His -6	-	expression tag
Ile -5	-	expression tag
Glu -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	250922.9
All*	Total formula weight	250922.9

*Water molecules are not included.