8VE6

(Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the frayed conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transthyretin	polymer	144	15902.5	4	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	ATTR,Prealbumin,TBPA
2	E (B)	2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID	non-polymer		330.1	1	Chemie (P2C)

Sequence modifications

A, B, C, D: 1 - 127 (UniProt: P02766)

PDB	External Database	Details
Met -16	-	expression tag
Asp -15	-	expression tag
Tyr -14	-	expression tag
Lys -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63610.0
Non-Polymers*	Number of molecules	1
	Total formula weight	330.1
All*	Total formula weight	63940.2

*Water molecules are not included.