8VDN
DNA Ligase 1 with nick dG:C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase 1 | polymer | 658 | 73042.3 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (human) | DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1 |
| 2 | B (C) | Downstream Oligo | polymer | 7 | 2138.4 | 1 | synthetic construct | ||
| 3 | C (B) | Upstream Oligo | polymer | 11 | 3405.2 | 1 | synthetic construct | ||
| 4 | D (D) | Template Oligo | polymer | 18 | 5446.5 | 1 | synthetic construct | ||
| 5 | E (C) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 6 | F, G, H, I (A, C, B, D) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 261 - 918 (UniProt: P18858)
| PDB | External Database | Details |
|---|---|---|
| Ala 346 | Glu 346 | engineered mutation |
| Ala 592 | Glu 592 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 84032.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 84379.7 |
