8VDG
Cryo-EM structure of human monoclonal antibody C74 targeting IT4VAR22 CIDRa1.7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Erythrocyte membrane protein 1 | polymer | 1153 | 133749.3 | 1 | UniProt (A3R6S4) Pfam (PF15447) Pfam (PF05424) Pfam (PF22672) Pfam (PF21807) Pfam (PF03011) | Plasmodium falciparum (malaria parasite P. falciparum) | |
| 2 | B (H) | C74 Fab heavy chain | polymer | 121 | 13441.0 | 1 | Homo sapiens | ||
| 3 | C (K) | C74 Fab kappa chain | polymer | 113 | 12178.5 | 1 | Homo sapiens |
Sequence modifications
A: 1 - 1153 (UniProt: A3R6S4)
| PDB | External Database | Details |
|---|---|---|
| Gln 109 | Arg 109 | conflict |
| Glu 329 | Gly 329 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 159368.8 | |
| All* | Total formula weight | 159368.8 |
