8VCY
Human TCR A2.13 in complex with DQ8-InsC8-15NPY
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | MHC class II HLA-DQ-alpha chain | polymer | 185 | 21124.5 | 1 | UniProt (Q30069) In PDB | Homo sapiens (human) | DQA1*03:01 (DQ8-alpha chain) |
2 | B | MHC class II HLA-DQ-beta-1 | polymer | 192 | 22605.4 | 1 | UniProt (O19707) In PDB | Homo sapiens (human) | DQB1*03:02 (DQ8-beta chain) |
3 | C | Hybrid insulin peptide (HIP; InsC8-15-NPY68-74) | polymer | 15 | 1433.5 | 1 | Homo sapiens (human) | ||
4 | D | T-CELL-RECEPTOR, TCR A2.13 alpha | polymer | 203 | 22633.2 | 1 | Homo sapiens (human) | ||
5 | E | T-CELL-RECEPTOR, TCR A2.13 beta | polymer | 239 | 27076.1 | 1 | Homo sapiens (human) | ||
6 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | A, B, D, E | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
8 | D, E | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
9 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: -1 - 181 (UniProt: Q30069)
PDB | External Database | Details |
---|---|---|
Cys 72 | Ile 75 | engineered mutation |
Ser 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 94872.8 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1282.8 | |
All* | Total formula weight | 96155.5 |