Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8VCV

Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GPC-C epitope)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Glycoprotein G1	polymer	259	29010.4	3	UniProt (P08669) Pfam (PF00798)	Lassa virus Josiah
2	D (H)	Rabbit polyclonal Fv heavy chain	polymer	125	10656.1	1		Oryctolagus cuniculus
3	E (L)	Rabbit polyclonal Fv light chain	polymer	110	9379.6	1		Oryctolagus cuniculus
4	F, G, H (a, b, c)	Glycoprotein G2	polymer	406	44765.0	3	UniProt (P08669) Pfam (PF00798)	Lassa virus Josiah	GP2
5	I (D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	BA, EA, FA, J, K... (Y, e, f, E, F...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	12	In PDB GlyTouCan (G42666HT)
7	P, U, W, X (M, R, T, U)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	4	In PDB GlyTouCan (G15407YE)
8	Q, R, V, Y (N, O, S, V)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	4	In PDB GlyTouCan (G21290RB)
9	AA (X)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G42227JK)
10	CA (Z)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G56014GC)
11	DA (d)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
12	GA, HA, IA, JA, KA... (A, B, C, a, b...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 259 (UniProt: P08669)

PDB	External Database	Details
Cys 207	Arg 207	conflict

a, b, c: 260 - 424 (UniProt: P08669)

PDB	External Database	Details
Pro 329	Glu 329	conflict
Cys 360	Gly 360	conflict
Gly 425	-	expression tag
Ser 426	-	expression tag
Gly 427	-	expression tag
Gly 428	-	expression tag
Ser 429	-	expression tag
Gly 430	-	expression tag
Gly 431	-	expression tag
Ser 432	-	expression tag
Gly 433	-	expression tag
Gly 434	-	expression tag
Ser 435	-	expression tag
Gly 436	-	expression tag
Gly 437	-	expression tag
Ser 438	-	expression tag
Glu 439	-	expression tag
Lys 440	-	expression tag
Ala 441	-	expression tag
Ala 442	-	expression tag
Lys 443	-	expression tag
Ala 444	-	expression tag
Glu 445	-	expression tag
Glu 446	-	expression tag
Ala 447	-	expression tag
Ala 448	-	expression tag
Arg 449	-	expression tag
Lys 450	-	expression tag
Met 451	-	expression tag
Glu 452	-	expression tag
Glu 453	-	expression tag
Leu 454	-	expression tag
Phe 455	-	expression tag
Lys 456	-	expression tag
Lys 457	-	expression tag
His 458	-	expression tag
Lys 459	-	expression tag
Ile 460	-	expression tag
Val 461	-	expression tag
Ala 462	-	expression tag
Val 463	-	expression tag
Leu 464	-	expression tag
Arg 465	-	expression tag
Ala 466	-	expression tag
Asn 467	-	expression tag
Ser 468	-	expression tag
Val 469	-	expression tag
Glu 470	-	expression tag
Glu 471	-	expression tag
Ala 472	-	expression tag
Ile 473	-	expression tag
Glu 474	-	expression tag
Lys 475	-	expression tag
Ala 476	-	expression tag
Val 477	-	expression tag
Ala 478	-	expression tag
Val 479	-	expression tag
Phe 480	-	expression tag
Ala 481	-	expression tag
Gly 482	-	expression tag
Gly 483	-	expression tag
Val 484	-	expression tag
His 485	-	expression tag
Leu 486	-	expression tag
Ile 487	-	expression tag
Glu 488	-	expression tag
Ile 489	-	expression tag
Thr 490	-	expression tag
Phe 491	-	expression tag
Thr 492	-	expression tag
Val 493	-	expression tag
Pro 494	-	expression tag
Asp 495	-	expression tag
Ala 496	-	expression tag
Asp 497	-	expression tag
Thr 498	-	expression tag
Val 499	-	expression tag
Ile 500	-	expression tag
Lys 501	-	expression tag
Ala 502	-	expression tag
Leu 503	-	expression tag
Ser 504	-	expression tag
Val 505	-	expression tag
Leu 506	-	expression tag
Lys 507	-	expression tag
Glu 508	-	expression tag
Lys 509	-	expression tag
Gly 510	-	expression tag
Ala 511	-	expression tag
Ile 512	-	expression tag
Ile 513	-	expression tag
Gly 514	-	expression tag
Ala 515	-	expression tag
Gly 516	-	expression tag
Thr 517	-	expression tag
Val 518	-	expression tag
Thr 519	-	expression tag
Ser 520	-	expression tag
Val 521	-	expression tag
Glu 522	-	expression tag
Gln 523	-	expression tag
Cys 524	-	expression tag
Arg 525	-	expression tag
Lys 526	-	expression tag
Ala 527	-	expression tag
Val 528	-	expression tag
Glu 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag
Ala 532	-	expression tag
Glu 533	-	expression tag
Phe 534	-	expression tag
Ile 535	-	expression tag
Val 536	-	expression tag
Ser 537	-	expression tag
Pro 538	-	expression tag
His 539	-	expression tag
Leu 540	-	expression tag
Asp 541	-	expression tag
Glu 542	-	expression tag
Glu 543	-	expression tag
Ile 544	-	expression tag
Ser 545	-	expression tag
Gln 546	-	expression tag
Phe 547	-	expression tag
Cys 548	-	expression tag
Lys 549	-	expression tag
Glu 550	-	expression tag
Lys 551	-	expression tag
Gly 552	-	expression tag
Val 553	-	expression tag
Phe 554	-	expression tag
Tyr 555	-	expression tag
Met 556	-	expression tag
Pro 557	-	expression tag
Gly 558	-	expression tag
Val 559	-	expression tag
Met 560	-	expression tag
Thr 561	-	expression tag
Pro 562	-	expression tag
Thr 563	-	expression tag
Glu 564	-	expression tag
Leu 565	-	expression tag
Val 566	-	expression tag
Lys 567	-	expression tag
Ala 568	-	expression tag
Met 569	-	expression tag
Lys 570	-	expression tag
Leu 571	-	expression tag
Gly 572	-	expression tag
His 573	-	expression tag
Asp 574	-	expression tag
Ile 575	-	expression tag
Leu 576	-	expression tag
Lys 577	-	expression tag
Leu 578	-	expression tag
Phe 579	-	expression tag
Pro 580	-	expression tag
Gly 581	-	expression tag
Glu 582	-	expression tag
Val 583	-	expression tag
Val 584	-	expression tag
Gly 585	-	expression tag
Pro 586	-	expression tag
Glu 587	-	expression tag
Phe 588	-	expression tag
Val 589	-	expression tag
Lys 590	-	expression tag
Ala 591	-	expression tag
Met 592	-	expression tag
Lys 593	-	expression tag
Gly 594	-	expression tag
Pro 595	-	expression tag
Phe 596	-	expression tag
Pro 597	-	expression tag
Asn 598	-	expression tag
Val 599	-	expression tag
Lys 600	-	expression tag
Phe 601	-	expression tag
Val 602	-	expression tag
Pro 603	-	expression tag
Thr 604	-	expression tag
Gly 605	-	expression tag
Gly 606	-	expression tag
Val 607	-	expression tag
Asp 608	-	expression tag
Leu 609	-	expression tag
Asp 610	-	expression tag
Asn 611	-	expression tag
Val 612	-	expression tag
Cys 613	-	expression tag
Glu 614	-	expression tag
Trp 615	-	expression tag
Phe 616	-	expression tag
Asp 617	-	expression tag
Ala 618	-	expression tag
Gly 619	-	expression tag
Val 620	-	expression tag
Leu 621	-	expression tag
Ala 622	-	expression tag
Val 623	-	expression tag
Gly 624	-	expression tag
Val 625	-	expression tag
Gly 626	-	expression tag
Asp 627	-	expression tag
Ala 628	-	expression tag
Leu 629	-	expression tag
Val 630	-	expression tag
Glu 631	-	expression tag
Gly 632	-	expression tag
Asp 633	-	expression tag
Pro 634	-	expression tag
Asp 635	-	expression tag
Glu 636	-	expression tag
Val 637	-	expression tag
Arg 638	-	expression tag
Glu 639	-	expression tag
Lys 640	-	expression tag
Ala 641	-	expression tag
Lys 642	-	expression tag
Glu 643	-	expression tag
Phe 644	-	expression tag
Val 645	-	expression tag
Glu 646	-	expression tag
Lys 647	-	expression tag
Ile 648	-	expression tag
Arg 649	-	expression tag
Gly 650	-	expression tag
Cys 651	-	expression tag
Thr 652	-	expression tag
Glu 653	-	expression tag
Gly 654	-	expression tag
Ser 655	-	expression tag
Leu 656	-	expression tag
Glu 657	-	expression tag
Trp 658	-	expression tag
Ser 659	-	expression tag
His 660	-	expression tag
Pro 661	-	expression tag
Gln 662	-	expression tag
Phe 663	-	expression tag
Glu 664	-	expression tag
Lys 665	-	expression tag

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	8
Polymers	Total formula weight	241361.9
Branched	Number of molecules	24
Branched	Total formula weight	13186.3
Non-Polymers*	Number of molecules	9
Non-Polymers*	Total formula weight	1990.9
All*	Total formula weight	256539.0

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)