8VCH

Voltage gated potassium ion channel Kv1.2 W366F, C-type inactivated

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium voltage-gated channel subfamily A member 2	polymer	536	60552.5	4	UniProt (P63142) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885)	Rattus norvegicus (Rat)	RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2
2	E, F (A, C)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)

Sequence modifications

A, B, C, D: 1 - 499 (UniProt: P63142)

PDB	External Database	Details
Met -36	-	initiating methionine
Ser -35	-	expression tag
Ala -34	-	expression tag
Trp -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
Pro -30	-	expression tag
Gln -29	-	expression tag
Phe -28	-	expression tag
Glu -27	-	expression tag
Lys -26	-	expression tag
Gly -25	-	expression tag
Gly -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Gly -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Ala -14	-	expression tag
Trp -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
Pro -10	-	expression tag
Gln -9	-	expression tag
Phe -8	-	expression tag
Glu -7	-	expression tag
Lys -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
His 15	Leu 15	conflict
Ser 198	Gly 198	conflict
Gln 207	Asn 207	conflict
Phe 366	Trp 366	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	242210.1
Non-Polymers*	Number of molecules	2
	Total formula weight	78.2
All*	Total formula weight	242288.3

*Water molecules are not included.