8VC7
Crystal Structure of Human BTN2A1 ectodomain in complex with Antagonist 2A1.9 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (D, A) | Human IgG1 Fragment Antibody Light Chain | polymer | 215 | 23258.8 | 2 | Homo sapiens | ||
| 2 | B, E (J, B) | Human IgG1 Fragment Antibody Heavy Chain | polymer | 233 | 24836.7 | 2 | Homo sapiens | ||
| 3 | C, F (C, E) | Butyrophilin subfamily 2 member A1 | polymer | 231 | 25725.3 | 2 | UniProt (Q7KYR7) Pfam (PF07686) Pfam (PF22705) | Homo sapiens (human) | |
| 4 | G, H, I, J, K (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
C, E: 1 - 219 (UniProt: Q7KYR7)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ser 219 | Cys 247 | engineered mutation |
| Gly 220 | - | expression tag |
| Ser 221 | - | expression tag |
| Gly 222 | - | expression tag |
| Leu 223 | - | expression tag |
| Glu 224 | - | expression tag |
| Val 225 | - | expression tag |
| Leu 226 | - | expression tag |
| Phe 227 | - | expression tag |
| Gln 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 147641.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 148747.5 |
