8V9M
Human Ornithine Aminotransferase cocrystallized with its inhibitor, (R)-3-amino-5,5-difluorocyclohex-1-ene-1-carboxylic acid.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 404 | 44860.3 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, F, I (A, B, C) | 3-fluoro-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]benzoic acid | non-polymer | 386.3 | 3 | Chemie (YR5) | |||
| 3 | E, G, H, J (A, B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | K, L, M (A, B, C) | water | water | 18.0 | 1132 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 134581.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1527.2 | |
| All* | Total formula weight | 136108.1 |
