8V7O
Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Hemagglutinin | polymer | 555 | 62494.7 | 3 | UniProt (Q00Q05) | Influenza A virus | X6 COBRA HA |
| 2 | D, E, F (H, I, J) | #58 heavy chain | polymer | 125 | 14052.6 | 3 | Homo sapiens (human) | ||
| 3 | G, H, I (L, M, N) | #58 light chain | polymer | 109 | 11797.2 | 3 | Homo sapiens (human) |
Sequence modifications
A, B, C: 1 - 502 (UniProt: Q00Q05)
| PDB | External Database | Details |
|---|---|---|
| Lys 208 | Arg 225 | conflict |
| Gly 503 | - | expression tag |
| Thr 504 | - | expression tag |
| Gly 505 | - | expression tag |
| Tyr 506 | - | expression tag |
| Ile 507 | - | expression tag |
| Pro 508 | - | expression tag |
| Glu 509 | - | expression tag |
| Ala 510 | - | expression tag |
| Pro 511 | - | expression tag |
| Arg 512 | - | expression tag |
| Asp 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Gln 515 | - | expression tag |
| Ala 516 | - | expression tag |
| Tyr 517 | - | expression tag |
| Val 518 | - | expression tag |
| Arg 519 | - | expression tag |
| Lys 520 | - | expression tag |
| Asp 521 | - | expression tag |
| Gly 522 | - | expression tag |
| Glu 523 | - | expression tag |
| Trp 524 | - | expression tag |
| Val 525 | - | expression tag |
| Leu 526 | - | expression tag |
| Leu 527 | - | expression tag |
| Ser 528 | - | expression tag |
| Thr 529 | - | expression tag |
| Phe 530 | - | expression tag |
| Leu 531 | - | expression tag |
| Gly 532 | - | expression tag |
| Ser 533 | - | expression tag |
| Gly 534 | - | expression tag |
| Leu 535 | - | expression tag |
| Asn 536 | - | expression tag |
| Asp 537 | - | expression tag |
| Ile 538 | - | expression tag |
| Phe 539 | - | expression tag |
| Glu 540 | - | expression tag |
| Ala 541 | - | expression tag |
| Gln 542 | - | expression tag |
| Lys 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Glu 545 | - | expression tag |
| Trp 546 | - | expression tag |
| His 547 | - | expression tag |
| Glu 548 | - | expression tag |
| Gly 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 265033.4 | |
| All* | Total formula weight | 265033.4 |
