8V6G
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase alpha catalytic subunit | polymer | 1127 | 129009.4 | 1 | UniProt (Q9DE46) Pfam (PF03104) Pfam (PF00136) Pfam (PF08996) | Xenopus laevis (African clawed frog) | DNA polymerase alpha catalytic subunit p180 |
| 2 | B (B) | DNA polymerase alpha subunit B | polymer | 601 | 67194.2 | 1 | UniProt (Q6DCZ1) Pfam (PF08418) Pfam (PF22062) Pfam (PF04042) | Xenopus laevis (African clawed frog) | |
| 3 | C (C) | DNA primase large subunit | polymer | 513 | 59673.8 | 1 | UniProt (A0A1L8G3G3) Pfam (PF04104) | Xenopus laevis (African clawed frog) | |
| 4 | D (D) | DNA primase | polymer | 423 | 49356.4 | 1 | UniProt (Q800A4) Pfam (PF01896) | Xenopus laevis (African clawed frog) | |
| 5 | E (E) | DNA template | polymer | 50 | 15458.9 | 1 | synthetic construct | ||
| 6 | F (F) | RNA primer | polymer | 9 | 2999.7 | 1 | synthetic construct | ||
| 7 | G, H, L (A, D) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 8 | I (A) | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) | |||
| 9 | J, M (A, F) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 10 | K (C) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) |
Sequence modifications
A: 335 - 1458 (UniProt: Q9DE46)
B: 1 - 598 (UniProt: Q6DCZ1)
D: 1 - 420 (UniProt: Q800A4)
| PDB | External Database | Details |
|---|---|---|
| Ser 332 | - | expression tag |
| Asn 333 | - | expression tag |
| Ala 334 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 323692.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1103.7 | |
| All* | Total formula weight | 324796.2 |
