8V5S

VZV glycoprotein E C-terminal domain (cleaved) in complex with human Fab 5A2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (H, A)	5A2 Fab Heavy Chain	polymer	242	26039.0	2		Homo sapiens (human)
2	B, D (L, B)	5A2 Fab Light Chain	polymer	210	22474.0	2		Homo sapiens (human)
3	E, F (C, D)	Envelope glycoprotein E	polymer	254	28010.8	2	UniProt (A0A1B1JEP3) UniProt (by SIFTS) (A6XEF7)	Human alphaherpesvirus 3 (Varicella-zoster virus)

Sequence modifications

C, D: 301 - 516 (UniProt: A0A1B1JEP3)

PDB	External Database	Details
Met 271	-	initiating methionine
Gly 272	-	expression tag
Thr 273	-	expression tag
Val 274	-	expression tag
Asn 275	-	expression tag
Lys 276	-	expression tag
Pro 277	-	expression tag
Val 278	-	expression tag
Val 279	-	expression tag
Gly 280	-	expression tag
Val 281	-	expression tag
Leu 282	-	expression tag
Met 283	-	expression tag
Gly 284	-	expression tag
Phe 285	-	expression tag
Gly 286	-	expression tag
Ile 287	-	expression tag
Ile 288	-	expression tag
Thr 289	-	expression tag
Gly 290	-	expression tag
Thr 291	-	expression tag
Leu 292	-	expression tag
Arg 293	-	expression tag
Ile 294	-	expression tag
Thr 295	-	expression tag
Asn 296	-	expression tag
Pro 297	-	expression tag
Val 298	-	expression tag
Arg 299	-	expression tag
Ala 300	-	expression tag
Gly 517	-	expression tag
Ser 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	153047.8
All*	Total formula weight	153047.8

*Water molecules are not included.