8V5O

Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA polymerase alpha catalytic subunit	polymer	1127	129009.4	1	UniProt (Q9DE46) Pfam (PF03104) Pfam (PF00136) Pfam (PF08996) In PDB	Xenopus laevis (African clawed frog)	DNA polymerase alpha catalytic subunit p180
2	B	DNA polymerase alpha subunit B	polymer	601	67194.2	1	UniProt (Q6DCZ1) Pfam (PF08418) Pfam (PF22062) Pfam (PF04042) In PDB	Xenopus laevis (African clawed frog)
3	C	DNA primase large subunit	polymer	513	59673.8	1	UniProt (A0A1L8G3G3) Pfam (PF04104) In PDB	Xenopus laevis (African clawed frog)
4	D	DNA primase	polymer	423	49356.4	1	UniProt (Q800A4) Pfam (PF01896) In PDB	Xenopus laevis (African clawed frog)
5	A, D	ZINC ION	non-polymer		65.4	3	Chemie (ZN)

Sequence modifications

A: 335 - 1458 (UniProt: Q9DE46)

PDB	External Database	Details
Ser 332	-	expression tag
Asn 333	-	expression tag
Ala 334	-	expression tag

B: 1 - 598 (UniProt: Q6DCZ1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

D: 1 - 420 (UniProt: Q800A4)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	305233.9
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	305430.1

*Water molecules are not included.