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8V5M

Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase alpha catalytic subunitpolymer1127129009.41UniProt (Q9DE46)
Pfam (PF03104)
Pfam (PF00136)
Pfam (PF08996)
Xenopus laevis (African clawed frog)DNA polymerase alpha catalytic subunit p180
2B
(B)
DNA polymerase alpha subunit Bpolymer60167194.21UniProt (Q6DCZ1)
Pfam (PF08418)
Pfam (PF22062)
Pfam (PF04042)
Xenopus laevis (African clawed frog)
3C
(C)
DNA primase large subunitpolymer51359673.81UniProt (A0A1L8G3G3)
Pfam (PF04104)
Xenopus laevis (African clawed frog)
4D
(D)
DNA primasepolymer42349356.41UniProt (Q800A4)
Pfam (PF01896)
Xenopus laevis (African clawed frog)
5E, F, G
(A, D)
ZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
A: 335 - 1458 (UniProt: Q9DE46)
PDBExternal DatabaseDetails
Ser 332-expression tag
Asn 333-expression tag
Ala 334-expression tag
B: 1 - 598 (UniProt: Q6DCZ1)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
D: 1 - 420 (UniProt: Q800A4)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight305233.9
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight305430.1
*Water molecules are not included.

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PDB entries from 2024-11-13

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