8V5G
Crystal Structure of Acetyl-CoA synthetase from Cryptococcus neoformans H99 in complex with an ethylsulfamide AMP inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Acetyl-coenzyme A synthetase | polymer | 694 | 77475.8 | 3 | UniProt (J9VFT1) Pfam (PF16177) Pfam (PF00501) Pfam (PF13193) In PDB | Cryptococcus neoformans var. grubii | |
2 | A, B | 5'-deoxy-5'-(ethylsulfamamido)adenosine | non-polymer | 373.4 | 2 | Chemie (YDO) | |||
3 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 680 (UniProt: J9VFT1)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
Glu -4 | - | expression tag |
Asn -3 | - | expression tag |
Leu -2 | - | expression tag |
Tyr -1 | - | expression tag |
Phe 0 | - | expression tag |
Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 232427.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 782.2 | |
All* | Total formula weight | 233209.5 |