8V4L

CCP5 in complex with microtubules class2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain
2	B, D (B, D)	Tubulin beta chain	polymer	450	50377.3	2	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Beta-tubulin
3	E (E)	Cytosolic carboxypeptidase-like protein 5	polymer	605	68229.5	1	UniProt (Q8NDL9) Pfam (PF18027) Pfam (PF00246)	Homo sapiens (human)
4	F, H, K, M (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)
5	G, L (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486)
6	I, N (B, D)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (G2P)
7	J (B)	GLUTAMIC ACID	non-polymer		147.1	1	Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032)
8	O (E)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

B, D: 1 - 445 (UniProt: P02554)
B, D: 501 - 505 (PDB: 8V4L)
E: 2 - 605 (UniProt: Q8NDL9)

PDB	External Database	Details
Asn 1	-	expression tag
Ala 516	Glu 516	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	269393.1
Non-Polymers*	Number of molecules	10
	Total formula weight	2398.5
All*	Total formula weight	271791.6

*Water molecules are not included.