8V4K

CCP5 in complex with microtubules class1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain
2	B, D (B, D)	Tubulin beta chain	polymer	445	49504.8	2	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Beta-tubulin
3	E (E)	Cytosolic carboxypeptidase-like protein 5	polymer	605	68229.5	1	UniProt (Q8NDL9) Pfam (PF18027) Pfam (PF00246)	Homo sapiens (human)
4	F, H, L, N (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	G, M (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	I, O (B, D)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (G2P)
7	J (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
8	K (B)	GLUTAMIC ACID	non-polymer		147.1	1	Chemie (GLU)

Sequence modifications

B, D: 1 - 445 (UniProt: P02554)

PDB	External Database	Details
Unk 431	Asp 431	conflict
Unk 432	Glu 432	conflict
Unk 433	Gln 433	conflict
Unk 434	Gly 434	conflict
Unk 436	Phe 436	conflict
Unk 437	Glu 437	conflict
Unk 438	Glu 438	conflict
Unk 439	Glu 439	conflict
Unk 440	Gly 440	conflict
Unk 441	Glu 441	conflict
Unk 442	Glu 442	conflict
Unk 443	Asp 443	conflict
Unk 444	Glu 444	conflict
Unk 445	Ala 445	conflict

E: 2 - 605 (UniProt: Q8NDL9)

PDB	External Database	Details
Asn 1	-	expression tag
Ala 516	Glu 516	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	267648.0
Non-Polymers*	Number of molecules	10
	Total formula weight	2398.5
All*	Total formula weight	270046.6

*Water molecules are not included.