8V2H
Cryo-EM structure of the KCa2.2 channel bound to inhibitor AP14145.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, B, C, D) | Small conductance calcium-activated potassium channel protein 2 | polymer | 361 | 41114.8 | 4 | UniProt (P70604) Pfam (PF03530) Pfam (PF07885) Pfam (PF02888) | Rattus norvegicus (Norway rat) | SK2,SKCa 2,SKCa2,KCa2.2 |
| 2 | B, D, F, H (E, F, G, H) | Calmodulin-1 | polymer | 146 | 16521.1 | 4 | UniProt (P0DP29) Pfam (PF13499) | Rattus norvegicus (Norway rat) | |
| 3 | I, J, K, L (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | M, N, O, P, Q... (E, F, G, H) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 230543.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 477.0 | |
| All* | Total formula weight | 231020.4 |
