8V1T
Herpes simplex virus 1 polymerase holoenzyme bound to DNA and acyclovir triphosphate in closed conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase | polymer | 1199 | 133614.3 | 1 | UniProt (H9E937) In PDB | Human alphaherpesvirus 1 strain KOS | |
2 | B | DNA polymerase processivity factor | polymer | 340 | 36346.2 | 1 | UniProt (H9E949) In PDB | Human alphaherpesvirus 1 strain KOS | Polymerase accessory protein |
3 | P | PRIMER DNA (32-MER) | polymer | 32 | 9866.4 | 1 | synthetic construct | ||
4 | T | TEMPLATE DNA (50-MER) | polymer | 50 | 15199.8 | 1 | synthetic construct | ||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
6 | A | ACYCLOVIR TRIPHOSPHATE | non-polymer | 465.1 | 1 | Chemie (AVP) | |||
7 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 43 - 1235 (UniProt: H9E937)
PDB | External Database | Details |
---|---|---|
His 37 | - | expression tag |
His 38 | - | expression tag |
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
His 42 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 195026.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 562.4 | |
All* | Total formula weight | 195589.0 |