8V1Q
Herpes simplex virus 1 polymerase holoenzyme bound to DNA in both open/closed conformations
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase | polymer | 1199 | 133614.3 | 1 | UniProt (H9E937) In PDB | Human alphaherpesvirus 1 strain KOS | |
2 | B | DNA polymerase processivity factor | polymer | 349 | 37275.1 | 1 | UniProt (A0A181ZFK4) In PDB | Human alphaherpesvirus 1 strain KOS | |
3 | P | Primer DNA | polymer | 32 | 9866.4 | 1 | synthetic construct | ||
4 | T | template DNA | polymer | 50 | 15223.8 | 1 | synthetic construct | ||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 43 - 1235 (UniProt: H9E937)
B: 2 - 340 (UniProt: A0A181ZFK4)
PDB | External Database | Details |
---|---|---|
His 37 | - | expression tag |
His 38 | - | expression tag |
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
His 42 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -8 | - | expression tag |
Pro -7 | - | expression tag |
Ile -6 | - | expression tag |
Ser -5 | - | expression tag |
Glu -4 | - | expression tag |
Phe -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Ser 0 | - | expression tag |
Arg 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 195979.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 48.6 | |
All* | Total formula weight | 196028.2 |