8V17
HIV-CA Disulfide linked Hexamer with inhibitor bound - exploration of a benzothiazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spacer peptide 1 | polymer | 229 | 25249.0 | 1 | UniProt (P12493) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (Q72497) | Human immunodeficiency virus 1 | SP1,p2 |
| 2 | B (A) | N-(1,3-benzothiazol-5-yl)-3,5-difluoro-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide | non-polymer | 520.5 | 1 | Chemie (Y4X) | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F (A) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 1 - 229 (UniProt: P12493)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25249.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 796.8 | |
| All* | Total formula weight | 26045.8 |
