8V0K
The structure of the native cardiac thin filament troponin core in Ca2+-bound partially activated state from the lower strand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Actin, alpha cardiac muscle 1 | polymer | 377 | 42064.9 | 2 | UniProt (B6VNT8) Pfam (PF00022) UniProt (by SIFTS) (A0A8W4F696) | Sus scrofa (pig) | Cardiac muscle alpha actin 1 |
| 2 | C (C) | Troponin C, slow skeletal and cardiac muscles | polymer | 161 | 18433.5 | 1 | UniProt (P63317) Pfam (PF13833) Pfam (PF13499) | Sus scrofa (pig) | TN-C |
| 3 | D (D) | Troponin I, cardiac muscle | polymer | 211 | 24092.7 | 1 | UniProt (A0A4X1V710) Pfam (PF11636) Pfam (PF00992) UniProt (by SIFTS) (A0A4X1V520) | Sus scrofa (pig) | Cardiac troponin I |
| 4 | E (E) | Troponin T2, cardiac type | polymer | 285 | 33941.7 | 1 | UniProt (A0A5G2Q8N0) Pfam (PF00992) | Sus scrofa (pig) | |
| 5 | F, G (F, G) | Tropomyosin alpha-1 chain | polymer | 284 | 32762.7 | 2 | UniProt (P42639) Pfam (PF00261) | Sus scrofa (pig) | Alpha-tropomyosin,Tropomyosin-1 |
| 6 | H, J (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 7 | I, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | L, M, N (C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 226123.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1023.2 | |
| All* | Total formula weight | 227146.3 |
