8V0B
Structure of TDP1 catalytic domain complexed with compound IB05
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosyl-DNA phosphodiesterase 1 | polymer | 461 | 52126.3 | 2 | UniProt (Q9NUW8) Pfam (PF06087) | Homo sapiens (human) | Tyr-DNA phosphodiesterase 1 |
| 2 | C, L (A, B) | 8-{4-[(fluorosulfonyl)oxy]phenyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | non-polymer | 363.3 | 2 | Chemie (YCI) | |||
| 3 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | J, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | K, P (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 676 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104252.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1591.7 | |
| All* | Total formula weight | 105844.4 |
