8UZV
Structure of TDP1 catalytic domain complexed with compound IB02
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosyl-DNA phosphodiesterase 1 | polymer | 461 | 52126.3 | 2 | UniProt (Q9NUW8) Pfam (PF06087) | Homo sapiens (human) | Tyr-DNA phosphodiesterase 1 |
| 2 | C, K (A, B) | 8-{[2-(fluorosulfonyl)ethyl]amino}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | non-polymer | 314.3 | 2 | Chemie (Y9G) | |||
| 3 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | J, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | N (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 597 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104252.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1387.5 | |
| All* | Total formula weight | 105640.2 |
