8UXY
Consensus olfactory receptor consOR1 bound to L-menthol and in complex with mini-Gs trimeric protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Z) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 2 | B (Y) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 370 | 40786.6 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (X) | GNAS complex locus | polymer | 261 | 30137.0 | 1 | UniProt (A0A804HIH4) Pfam (PF00503) UniProt (by SIFTS) (P63092) | Homo sapiens (human) | |
| 4 | D (N) | Nanobody 35 | polymer | 145 | 15931.7 | 1 | Lama glama | ||
| 5 | E (A) | consOR1 | polymer | 321 | 35925.1 | 1 | synthetic construct | ||
| 6 | F (A) | (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol | non-polymer | 156.3 | 1 | Chemie (XUQ) PubChem (45056) PubChem (165675) PubChem (439263) PubChem (1254) PubChem (16666) PubChem (19243) PubChem (19244) PubChem (12141429) PubChem (1715097) PubChem (5319369) PubChem (6432468) PubChem (6566020) PubChem (11228933) PubChem (11815981) PubChem (12076118) PubChem (12285346) PubChem (12285348) PubChem (12285349) PubChem (67414864) PubChem (68026467) PubChem (12039947) PubChem (12285347) PubChem (23617692) PubChem (57110971) PubChem (67988893) PubChem (67988905) |
Sequence modifications
Y: 2 - 340 (UniProt: P62873)
X: 204 - 394 (UniProt: A0A804HIH4)
| PDB | External Database | Details |
|---|---|---|
| Met -29 | - | initiating methionine |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Glu -21 | - | expression tag |
| Val -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Phe -18 | - | expression tag |
| Gln -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Gln -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Arg -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Val -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Gln 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Asn 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Lys 8 | - | expression tag |
| Thr 9 | - | expression tag |
| Glu 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Gln 12 | - | expression tag |
| Arg 13 | - | expression tag |
| Asn 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Gln 19 | - | expression tag |
| Arg 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Lys 24 | - | expression tag |
| Lys 25 | - | expression tag |
| Ile 26 | - | expression tag |
| Glu 27 | - | expression tag |
| Lys 28 | - | expression tag |
| Gln 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Gln 31 | - | expression tag |
| Lys 32 | - | expression tag |
| Asp 33 | - | expression tag |
| Lys 34 | - | expression tag |
| Gln 35 | - | expression tag |
| Val 36 | - | expression tag |
| Tyr 37 | - | expression tag |
| Arg 38 | - | expression tag |
| Ala 39 | - | expression tag |
| Thr 40 | - | expression tag |
| His 41 | - | expression tag |
| Arg 42 | - | expression tag |
| Leu 43 | - | expression tag |
| Leu 44 | - | expression tag |
| Leu 45 | - | expression tag |
| Leu 46 | - | expression tag |
| Gly 47 | - | expression tag |
| Ala 48 | - | expression tag |
| Asp 49 | - | expression tag |
| Asn 50 | - | expression tag |
| Ser 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Lys 53 | - | expression tag |
| Ser 54 | - | expression tag |
| Thr 55 | - | expression tag |
| Ile 56 | - | expression tag |
| Val 57 | - | expression tag |
| Lys 58 | - | expression tag |
| Gln 59 | - | expression tag |
| Met 60 | - | expression tag |
| Arg 61 | - | expression tag |
| Ile 193 | - | expression tag |
| Leu 194 | - | expression tag |
| His 195 | - | expression tag |
| Gly 196 | - | expression tag |
| Gly 197 | - | expression tag |
| Ser 198 | - | expression tag |
| Gly 199 | - | expression tag |
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| Gly 202 | - | expression tag |
| Gly 203 | - | expression tag |
| Asp 249 | Ala 140 | conflict |
| Asp 252 | Ser 143 | conflict |
| - | Met 146 | deletion |
| - | Val 147 | deletion |
| - | Ile 148 | deletion |
| - | Arg 149 | deletion |
| - | Glu 150 | deletion |
| - | Asp 151 | deletion |
| - | Asn 152 | deletion |
| - | Gln 153 | deletion |
| - | Thr 154 | deletion |
| - | Asn 155 | deletion |
| Ala 372 | Ile 263 | conflict |
| Ile 375 | Val 266 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 130641.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 156.3 | |
| All* | Total formula weight | 130797.8 |
