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8UW0

Escherichia coli DHFR bound to NADP+ and folate, 17.2 MGy dose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductasepolymer15918067.31UniProt (C3TR70)
Pfam (PF00186)
UniProt (by SIFTS) (P0ABQ4)
Escherichia coli
2B
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
3C
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
4D, E, F, G
(A)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
5H
(A)
waterwater18.0366Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18067.3
Non-Polymers*Number of molecules6
Total formula weight1404.6
All*Total formula weight19471.9
*Water molecules are not included.

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PDB entries from 2026-02-11

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