8UVA
M. tuberculosis CTP synthase bound to inhibitor GSK735826A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CTP synthase | polymer | 592 | 64542.8 | 4 | UniProt (A0A045H225) | Mycobacterium tuberculosis | |
| 2 | E, I, M, Q (A, B, C, D) | GLUTAMINE | non-polymer | 146.1 | 4 | Chemie (GLN) | |||
| 3 | F, J, P, T (A, B, C, D) | N-[(4M)-4-(pyridin-2-yl)-1,3-thiazol-2-yl]-2H-[1,3]dioxolo[4,5-f][1,3]benzothiazol-6-amine | non-polymer | 354.4 | 4 | Chemie (XMW) | |||
| 4 | G, K, N, R (A, B, C, D) | URIDINE 5'-TRIPHOSPHATE | non-polymer | 484.1 | 4 | Chemie (UTP) | |||
| 5 | H, L, O, S (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence modifications
A, B, C, D: 1 - 586 (UniProt: A0A045H225)
| PDB | External Database | Details |
|---|---|---|
| His 587 | - | expression tag |
| His 588 | - | expression tag |
| His 589 | - | expression tag |
| His 590 | - | expression tag |
| His 591 | - | expression tag |
| His 592 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258171.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 4036.0 | |
| All* | Total formula weight | 262207.2 |
