8UV9

M. tuberculosis CTP synthase bound to inhibitor GSK1570606A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CTP synthase	polymer	592	64542.8	4	UniProt (A0A045H225) Pfam (PF06418) Pfam (PF00117) UniProt (by SIFTS) (P9WHK7)	Mycobacterium tuberculosis
2	E, J, O, R (A, B, C, D)	GLUTAMINE	non-polymer		146.1	4	Chemie (GLN)
3	F, K, Q, T (A, B, C, D)	2-(4-fluorophenyl)-~{N}-(4-pyridin-2-yl-1,3-thiazol-2-yl)ethanamide	non-polymer		313.3	4	Chemie (Q2N)
4	G, I, L, N (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	H, M, P, S (A, B, C, D)	URIDINE 5'-TRIPHOSPHATE	non-polymer		484.1	4	Chemie (UTP)

Sequence modifications

A, B, C, D: 1 - 586 (UniProt: A0A045H225)

PDB	External Database	Details
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	258171.2
Non-Polymers*	Number of molecules	16
	Total formula weight	3871.8
All*	Total formula weight	262042.9

*Water molecules are not included.