8UUP
Structure of the Measles virus Fusion protein in the pre-fusion conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Fusion glycoprotein F0 | polymer | 112 | 12498.8 | 3 | UniProt (Q786F3) | Measles virus strain Ichinose-B95a | |
| 2 | B, D, F (B, D, F) | Fusion glycoprotein F0 | polymer | 420 | 44898.8 | 3 | UniProt (Q786F3) Pfam (PF00523) | Measles virus strain Ichinose-B95a | |
| 3 | G (G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | H, J, L (H, J, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, K (I, K) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 6 | M, N (A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
B, D, F: 113 - 495 (UniProt: Q786F3)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | Glu 170 | engineered mutation |
| Gly 455 | Glu 455 | engineered mutation |
| Gly 496 | - | expression tag |
| Val 497 | - | expression tag |
| Asp 498 | - | expression tag |
| Asp 499 | - | expression tag |
| Asp 500 | - | expression tag |
| Asp 501 | - | expression tag |
| Lys 502 | - | expression tag |
| Ala 503 | - | expression tag |
| Gly 504 | - | expression tag |
| Trp 505 | - | expression tag |
| Ser 506 | - | expression tag |
| His 507 | - | expression tag |
| Pro 508 | - | expression tag |
| Gln 509 | - | expression tag |
| Phe 510 | - | expression tag |
| Glu 511 | - | expression tag |
| Lys 512 | - | expression tag |
| Gly 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Ser 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Ser 520 | - | expression tag |
| Gly 521 | - | expression tag |
| Gly 522 | - | expression tag |
| Gly 523 | - | expression tag |
| Ser 524 | - | expression tag |
| Trp 525 | - | expression tag |
| Ser 526 | - | expression tag |
| His 527 | - | expression tag |
| Pro 528 | - | expression tag |
| Gln 529 | - | expression tag |
| Phe 530 | - | expression tag |
| Glu 531 | - | expression tag |
| Lys 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 172192.8 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3681.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 176316.6 |
