8UUI
X-ray structure of Interleukin-23 in complex with peptide 23-446
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Interleukin-23 subunit alpha | polymer | 176 | 19525.0 | 1 | UniProt (Q9NPF7) Pfam (PF16649) | Homo sapiens (human) | |
| 2 | B (A) | Interleukin-12 subunit beta | polymer | 307 | 34811.0 | 1 | UniProt (P29460) Pfam (PF10420) | Homo sapiens (human) | IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,NKSF2 |
| 3 | C (D) | peptide 23-446 | polymer | 20 | 2620.9 | 1 | unidentified | ||
| 4 | D (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 5 | E, F (B, A) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
B: 20 - 189 (UniProt: Q9NPF7)
| PDB | External Database | Details |
|---|---|---|
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| His 193 | - | expression tag |
| His 194 | - | expression tag |
| His 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56957.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| All* | Total formula weight | 57705.6 |
