8UUG
SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun12303
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Papain-like protease nsp3 | polymer | 318 | 35943.8 | 1 | UniProt (P0DTD1) Pfam (PF08715) In PDB | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus) | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
| 2 | A | N-[(1R)-1-{(3M,5M)-3-[1-(difluoromethyl)-1H-pyrazol-4-yl]-5-[1-(methoxymethyl)-1H-pyrazol-4-yl]phenyl}ethyl]-5-[2-(dimethylamino)ethoxy]-2-methylbenzamide | non-polymer | 552.6 | 1 | Chemie (XXW) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | A | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35943.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1172.6 | |
| All* | Total formula weight | 37116.4 |
