8UTU
KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | K | Kinesin-like protein KIF1A | polymer | 438 | 49304.5 | 1 | UniProt (Q12756) Pfam (PF00225) In PDB | Homo sapiens (human) | |
2 | A, E | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
3 | B | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 1 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (pig) | |
4 | K, A, E | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
5 | K | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
6 | A, E | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
7 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
8 | B | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) |
Sequence modifications
K: 1 - 393 (UniProt: Q12756)
PDB | External Database | Details |
---|---|---|
Leu 305 | Pro 305 | engineered mutation |
Gly 394 | - | linker |
Ala 395 | - | linker |
Gly 396 | - | linker |
Val 397 | - | linker |
Lys 398 | - | linker |
Gln 399 | - | linker |
Leu 400 | - | linker |
Glu 401 | - | linker |
Asp 402 | - | linker |
Lys 403 | - | linker |
Val 404 | - | linker |
Glu 405 | - | linker |
Glu 406 | - | linker |
Leu 407 | - | linker |
Ala 408 | - | linker |
Ser 409 | - | linker |
Lys 410 | - | linker |
Asn 411 | - | linker |
Tyr 412 | - | linker |
His 413 | - | linker |
Leu 414 | - | linker |
Glu 415 | - | linker |
Asn 416 | - | linker |
Glu 417 | - | linker |
Val 418 | - | linker |
Ala 419 | - | linker |
Arg 420 | - | linker |
Leu 421 | - | linker |
Lys 422 | - | linker |
Lys 423 | - | linker |
Leu 424 | - | linker |
Val 425 | - | linker |
Glu 426 | - | expression tag |
Phe 427 | - | expression tag |
Thr 428 | - | expression tag |
Ser 429 | - | expression tag |
Ala 430 | - | expression tag |
Trp 431 | - | expression tag |
Ser 432 | - | expression tag |
His 433 | - | expression tag |
Pro 434 | - | expression tag |
Gln 435 | - | expression tag |
Phe 436 | - | expression tag |
Glu 437 | - | expression tag |
Lys 438 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 199713.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2922.6 | |
All* | Total formula weight | 202635.8 |