8USW

CNQX-bound GluN1a-3A NMDA receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Glutamate receptor ionotropic, NMDA 1	polymer	847	95041.7	2	UniProt (P35439) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB	Homo sapiens (human)
2	B, D	Glutamate receptor ionotropic, NMDA 3A	polymer	939	104837.2	2	UniProt (Q8TCU5) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB	Homo sapiens (human)
3	A, C	7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile	non-polymer		232.2	2	Chemie (DQC)

Sequence modifications

A, C: 1 - 847 (UniProt: P35439)

PDB	External Database	Details
Ser 22	Cys 22	conflict
Ser 159	Asn 159	conflict
Lys 212	Arg 212	conflict
Leu 267	Ile 267	conflict
Val 657	Leu 657	conflict
Cys 810	Phe 810	conflict
Asn 844	Arg 844	conflict
Gly 845	Arg 845	conflict
Ala 846	Lys 846	conflict

B, D: 38 - 967 (UniProt: Q8TCU5)

PDB	External Database	Details
Cys 676	Thr 676	conflict
Thr 968	-	expression tag
Glu 969	-	expression tag
Thr 970	-	expression tag
Ser 971	-	expression tag
Gln 972	-	expression tag
Val 973	-	expression tag
Ala 974	-	expression tag
Pro 975	-	expression tag
Ala 976	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	399757.7
Non-Polymers*	Number of molecules	2
	Total formula weight	464.3
All*	Total formula weight	400222.0

*Water molecules are not included.