8UR2

Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I41 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	MACROPHAGE MIGRATION INHIBITORY FACTOR	polymer	136	14842.8	6	UniProt (A2DXT4) Pfam (PF01187)	Trichomonas vaginalis G3
2	G (B)	IODIDE ION	non-polymer		126.9	1	Chemie (IOD)
3	H (B)	PYRUVIC ACID	non-polymer		88.1	1	Chemie (PYR)
4	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	167	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 14 - 128 (UniProt: A2DXT4)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Gly 2	-	expression tag
Thr 3	-	expression tag
Leu 4	-	expression tag
Glu 5	-	expression tag
Ala 6	-	expression tag
Gln 7	-	expression tag
Thr 8	-	expression tag
Gln 9	-	expression tag
Gly 10	-	expression tag
Pro 11	-	expression tag
Gly 12	-	expression tag
Ser 13	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	89056.8
Non-Polymers*	Number of molecules	2
	Total formula weight	215.0
All*	Total formula weight	89271.8

*Water molecules are not included.