8UQ7
Alzheimer's disease PHF complexed with PET ligand MK-6240
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, B, C, D, E...) | Microtubule-associated protein tau | polymer | 75 | 8184.4 | 6 | UniProt (P10636) Pfam (PF00418) | Homo sapiens (human) | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
2 | G, H, I, J, K... (A, B, C, D) | 6-fluoro-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine | non-polymer | 278.3 | 6 | Chemie (X6R) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 49106.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1669.7 | |
All* | Total formula weight | 50776.2 |