8UP2

Murine Fab JAR 4 bound to meningococcal Factor H binding protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Human-mouse chimeric immunoglobulin heavy chain, Fd fragment	polymer	223	23920.9	2		Mus musculus (mouse)
2	B, E (B, E)	Human-mouse chimeric immunoglobulin, kappa light chain	polymer	220	24198.2	2		Mus musculus (mouse)
3	C, F (C, F)	Factor H binding protein, sequence variant ID 1	polymer	257	27699.9	2	UniProt (Q6VRZ6) Pfam (PF20937) Pfam (PF08794) UniProt (by SIFTS) (Q9JXV4)	Neisseria meningitidis
4	G, I (C, F)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	H (D)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6	J, K, L, M, N... (A, B, C, D, E...)	water	water		18.0	1015	Chemie (HOH)

Sequence modifications

C, F: 8 - 255 (UniProt: Q6VRZ6)

PDB	External Database	Details
Met 7	-	initiating methionine
Leu 256	-	expression tag
Glu 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag
His 263	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	151637.9
Non-Polymers*	Number of molecules	3
	Total formula weight	243.2
All*	Total formula weight	151881.1

*Water molecules are not included.