8UN0

Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with cracked and closed PCNA (state 7)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chromosome transmission fidelity protein 18 homolog	polymer	975	107524.0	1	UniProt (Q8WVB6) Pfam (PF00004)	Homo sapiens (human)
2	B (B)	Replication factor C subunit 2	polymer	354	39203.2	1	UniProt (P35250) Pfam (PF00004) Pfam (PF08542)	Homo sapiens (human)	Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RFC40
3	C (C)	Replication factor C subunit 5	polymer	340	38545.5	1	UniProt (P40937) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542)	Homo sapiens (human)	Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RFC36
4	D (D)	Replication factor C subunit 4	polymer	363	39735.7	1	UniProt (P35249) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542)	Homo sapiens (human)
5	E (E)	Replication factor C subunit 3	polymer	356	40614.3	1	UniProt (P40938) Pfam (PF13177) Pfam (PF21960) Pfam (PF22534)	Homo sapiens (human)	Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RFC38
6	F, G, H (F, G, H)	Proliferating cell nuclear antigen	polymer	261	28795.8	3	UniProt (P12004) Pfam (PF00705) Pfam (PF02747)	Homo sapiens (human)	PCNA,Cyclin
7	I (I)	DNA (40-MER)	polymer	40	12214.8	1		synthetic construct
8	J (J)	DNA (20-MER)	polymer	20	6136.0	1		synthetic construct
9	K, M, O, Q (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
10	L, N, P, R (A, B, C, D)	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	4	Chemie (AGS)
11	S (E)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	370360.8
Non-Polymers*	Number of molecules	9
	Total formula weight	2617.4
All*	Total formula weight	372978.2

*Water molecules are not included.