8UMU
Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state (state 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chromosome transmission fidelity protein 18 homolog | polymer | 983 | 108521.0 | 1 | UniProt (Q8WVB6) Pfam (PF00004) | Homo sapiens (human) | |
| 2 | B (B) | Replication factor C subunit 2 | polymer | 354 | 39203.2 | 1 | UniProt (P35250) Pfam (PF00004) Pfam (PF08542) | Homo sapiens (human) | Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RFC40 |
| 3 | C (C) | Replication factor C subunit 5 | polymer | 340 | 38545.5 | 1 | UniProt (P40937) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542) | Homo sapiens (human) | Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RFC36 |
| 4 | D (D) | Replication factor C subunit 4 | polymer | 363 | 39735.7 | 1 | UniProt (P35249) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542) | Homo sapiens (human) | |
| 5 | E (E) | Replication factor C subunit 3 | polymer | 356 | 40614.3 | 1 | UniProt (P40938) Pfam (PF13177) Pfam (PF21960) Pfam (PF22534) | Homo sapiens (human) | Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RFC38 |
| 6 | F, G, H (F, G, H) | Proliferating cell nuclear antigen | polymer | 261 | 28795.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA,Cyclin |
| 7 | I, K, M (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 8 | J, L, N (A, B, C) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 3 | Chemie (AGS) | |||
| 9 | O (E) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A: 1 - 975 (UniProt: Q8WVB6)
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Lys 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 353007.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2069.9 | |
| All* | Total formula weight | 355076.9 |
