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8UMT

Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding state (state 2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Chromosome transmission fidelity protein 18 homologpolymer975107524.01UniProt (Q8WVB6)
Pfam (PF00004)
Homo sapiens (human)
2B
(B)
Replication factor C subunit 2polymer35439203.21UniProt (P35250)
Pfam (PF00004)
Pfam (PF08542)
Homo sapiens (human)Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RFC40
3C
(C)
Replication factor C subunit 5polymer34038545.51UniProt (P40937)
Pfam (PF00004)
Pfam (PF21960)
Pfam (PF08542)
Homo sapiens (human)Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RFC36
4D
(D)
Replication factor C subunit 4polymer36339735.71UniProt (P35249)
Pfam (PF00004)
Pfam (PF21960)
Pfam (PF08542)
Homo sapiens (human)
5E
(E)
Replication factor C subunit 3polymer35640614.31UniProt (P40938)
Pfam (PF13177)
Pfam (PF21960)
Pfam (PF22534)
Homo sapiens (human)Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RFC38
6F, G, H
(F, G, H)
Proliferating cell nuclear antigenpolymer26128795.83UniProt (P12004)
Pfam (PF00705)
Pfam (PF02747)
Homo sapiens (human)PCNA,Cyclin
7I, K, M
(B, C, D)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
8J, L, N
(B, C, D)
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERnon-polymer523.23Chemie (AGS)
9O
(E)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight352010.0
Non-Polymers*Number of molecules7
Total formula weight2069.9
All*Total formula weight354079.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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