8UJY
Crystal structure of human WD repeat-containing protein 5 in complex with 4-(3,5-dimethoxybenzyl)-9-(4-fluoro-2-methylphenyl)-7-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (compound 8)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat-containing protein 5 | polymer | 312 | 34289.9 | 2 | UniProt (P61964) Pfam (PF25175) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | C, D (A, B) | (9P)-4-[(3,5-dimethoxyphenyl)methyl]-9-(4-fluoro-2-methylphenyl)-7-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-3,4-dihydro-1,4-benzoxazepin-5(2H)-one | non-polymer | 530.6 | 2 | Chemie (VV3) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 480 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68579.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1061.2 | |
| All* | Total formula weight | 69641.0 |
