8UJM

Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex with magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1	polymer	276	31697.4	2	UniProt (O95476) UniProt (H3BUT5) Pfam (PF03031) UniProt (by SIFTS) (Q8N9A8)	Homo sapiens (human)	Transmembrane protein 188
2	C, D (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	E, F (A, B)	water	water		18.0	275	Chemie (HOH)

Sequence modifications

A, B: 2 - 206 (UniProt: O95476)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 207	-	linker
Ser 208	-	linker
Ala 209	-	linker
Lys 210	-	linker
Gly 211	-	linker
Ser 212	-	linker
Glu 213	-	linker
Ser 214	-	linker
Asn 215	-	linker
Ser 216	-	linker
Leu 217	-	linker
Glu 218	-	linker
Gln 219	-	linker
Ala 220	-	linker
Glu 221	-	linker
Asp 222	-	linker
Leu 223	-	linker
Lys 224	-	linker
Ala 225	-	linker
Phe 226	-	linker
Glu 227	-	linker
Arg 228	-	linker
Arg 229	-	linker
Leu 230	-	linker
Thr 231	-	linker
Glu 232	-	linker
Tyr 233	-	linker
Ile 234	-	linker
His 235	-	linker
Cys 236	-	linker
Leu 237	-	linker
Gln 238	-	linker

A, B: 239 - 270 (UniProt: H3BUT5)

PDB	External Database	Details
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63394.9
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	63443.5

*Water molecules are not included.