8UJF
X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycosyl transferase | polymer | 563 | 63514.1 | 2 | UniProt (A0A125YMZ8) Pfam (PF00535) Pfam (PF02709) Pfam (PF00652) In PDB | Toxoplasma gondii ME49 | |
| 2 | E | Mucin-5AC | polymer | 16 | 1501.6 | 1 | UniProt (P98088) In PDB | Homo sapiens | MUC-5AC,Gastric mucin,Major airway glycoprotein,Mucin-5 subtype AC,tracheobronchial,Tracheobronchial mucin,TBM |
| 3 | A, B | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 5 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B: 74 - 635 (UniProt: A0A125YMZ8)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Ser 297 | Gly 297 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 128529.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1249.3 | |
| All* | Total formula weight | 129779.1 |
