8UGR
In-situ structure of typeX supercomplex in respiratory chain (composite)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, DC (1A, 5A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13026.5 | 2 | UniProt (O79880) Pfam (PF00507) | Sus scrofa (pig) | NADH dehydrogenase subunit 3 |
| 2 | B, EC (1B, 5B) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | polymer | 258 | 28500.2 | 2 | UniProt (A0A4X1VVS8) Pfam (PF01058) | Sus scrofa (pig) | |
| 3 | C, FC (1C, 5C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 264 | 30241.4 | 2 | UniProt (A0A286ZNN4) Pfam (PF00329) | Sus scrofa (pig) | |
| 4 | D, GC (1D, 5D) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 466 | 52953.8 | 2 | UniProt (A0A8D1TTB3) Pfam (PF00346) UniProt (by SIFTS) (A0A8D0QM68) | Sus scrofa (pig) | Complex I-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 5 | E, HC (1E, 5E) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 249 | 27439.5 | 2 | UniProt (A0A4X1VRV3) Pfam (PF01257) | Sus scrofa (pig) | |
| 6 | F, IC (1F, 5F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50637.8 | 2 | UniProt (A0A4X1SZP7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Sus scrofa (pig) | |
| 7 | G, JC (1G, 5G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79627.4 | 2 | UniProt (A0A287ARY3) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) Pfam (PF13510) | Sus scrofa (pig) | |
| 8 | H, KC (1H, 5H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35619.4 | 2 | UniProt (A0A0U1RS44) Pfam (PF00146) | Sus scrofa (pig) | |
| 9 | I, LC (1I, 5I) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 239 | 27135.0 | 2 | UniProt (A0A286ZUN9) Pfam (PF12838) | Sus scrofa (pig) | |
| 10 | J, MC (1J, 5J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 2 | UniProt (O79882) Pfam (PF00499) | Sus scrofa (pig) | |
| 11 | K, NC (1K, 5K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10855.3 | 2 | UniProt (P56632) Pfam (PF00420) | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 12 | L, OC (1L, 5L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68723.5 | 2 | UniProt (Q9TDR1) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Sus scrofa (pig) | NADH dehydrogenase subunit 5 |
| 13 | M, PC (1M, 5M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51887.4 | 2 | UniProt (O79881) Pfam (PF01059) Pfam (PF00361) | Sus scrofa (pig) | NADH dehydrogenase subunit 4 |
| 14 | N, QC (1N, 5N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39105.5 | 2 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 15 | O, RC (1O, 5O) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 357 | 40476.1 | 2 | UniProt (F1SIS9) Pfam (PF01712) | Sus scrofa (pig) | |
| 16 | P, SC (1P, 5P) | NADH:ubiquinone oxidoreductase subunit A9 | polymer | 377 | 42606.3 | 2 | UniProt (A0A4X1ULW2) Pfam (PF01370) | Sus scrofa (pig) | |
| 17 | Q, TC (1Q, 5Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 175 | 19746.5 | 2 | UniProt (A0A4X1SN37) Pfam (PF04800) | Sus scrofa (pig) | |
| 18 | R, UC (1R, 5R) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 123 | 13349.0 | 2 | UniProt (A0A4X1THU2) Pfam (PF10276) | Sus scrofa (pig) | |
| 19 | S, VC (1S, 5S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 11099.8 | 2 | UniProt (A0A8D1FN21) Pfam (PF05047) | Sus scrofa (pig) | |
| 20 | T, U, WC, XC (1T, 1U, 5T, 5U) | NADH:ubiquinone oxidoreductase subunit AB1 | polymer | 156 | 17338.2 | 4 | UniProt (A0A8D1KH26) Pfam (PF00550) | Sus scrofa (pig) | |
| 21 | V, YC (1V, 5V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1 | polymer | 116 | 13321.6 | 2 | UniProt (A0A8D0UWW0) Pfam (PF04716) | Sus scrofa (pig) | |
| 22 | W, ZC (1W, 5W) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 128 | 14953.3 | 2 | UniProt (A0A480VKQ8) Pfam (PF05347) | Sus scrofa (pig) | |
| 23 | AD, X (1X, 5X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 172 | 20064.1 | 2 | UniProt (A0A8D0K6B5) Pfam (PF06747) | Sus scrofa (pig) | |
| 24 | BD, Y (1Y, 5Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 141 | 14686.9 | 2 | UniProt (I3LGM4) Pfam (PF02466) | Sus scrofa (pig) | |
| 25 | CD, Z (1Z, 5Z) | NADH:ubiquinone oxidoreductase subunit A13 | polymer | 144 | 16911.6 | 2 | UniProt (A0A8D0K655) Pfam (PF06212) | Sus scrofa (pig) | |
| 26 | AA, DD (1a, 5a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8034.4 | 2 | UniProt (A0A8D0TJQ4) Pfam (PF15879) | Sus scrofa (pig) | |
| 27 | BA, ED (1b, 5b) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 84 | 9225.6 | 2 | UniProt (A0A4X1VQ42) Pfam (PF14987) | Sus scrofa (pig) | |
| 28 | CA, FD (1c, 5c) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 76 | 8664.1 | 2 | UniProt (A0A8D0J7S2) Pfam (PF15088) | Sus scrofa (pig) | Complex I-KFYI,NADH-ubiquinone oxidoreductase KFYI subunit |
| 29 | DA, GD (1d, 5d) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 122 | 14327.7 | 2 | UniProt (A0A480JRW3) Pfam (PF06374) | Sus scrofa (pig) | |
| 30 | EA, HD (1e, 5e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 106 | 12506.6 | 2 | UniProt (A0A4X1VX77) Pfam (PF10200) | Sus scrofa (pig) | |
| 31 | FA, ID (1f, 5f) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 58 | 7044.3 | 2 | UniProt (A0A8D2CGH8) Pfam (PF08040) UniProt (by SIFTS) (A0A8D1IZ33) | Sus scrofa (pig) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 32 | GA, JD (1g, 5g) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 154 | 17384.7 | 2 | UniProt (A0A8D1EYI7) Pfam (PF10183) | Sus scrofa (pig) | |
| 33 | HA, KD (1h, 5h) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 189 | 21587.0 | 2 | UniProt (F1SGC6) Pfam (PF09781) | Sus scrofa (pig) | |
| 34 | IA, LD (1i, 5i) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 128 | 15498.0 | 2 | UniProt (A0A4X1UIV8) Pfam (PF09782) | Sus scrofa (pig) | Complex I-B17,NADH-ubiquinone oxidoreductase B17 subunit |
| 35 | JA, MD (1j, 5j) | NADH:ubiquinone oxidoreductase subunit B2 | polymer | 105 | 11939.4 | 2 | UniProt (A0A8D1G9F4) Pfam (PF14813) | Sus scrofa (pig) | |
| 36 | KA, ND (1k, 5k) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 98 | 11128.5 | 2 | UniProt (A0A4X1VD84) Pfam (PF08122) | Sus scrofa (pig) | |
| 37 | LA, OD (1l, 5l) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 186 | 21658.4 | 2 | UniProt (B8Y651) Pfam (PF05821) | Sus scrofa (pig) | |
| 38 | MA, PD (1m, 5m) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 129 | 15117.4 | 2 | UniProt (A0A4X1T6M0) Pfam (PF07225) | Sus scrofa (pig) | |
| 39 | NA, QD (1n, 5n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 179 | 21864.9 | 2 | UniProt (K7GSE5) Pfam (PF05347) | Sus scrofa (pig) | |
| 40 | OA, RD (1o, 5o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 136 | 16356.7 | 2 | UniProt (F1SCH1) Pfam (PF05676) | Sus scrofa (pig) | Complex I-B18,NADH-ubiquinone oxidoreductase B18 subunit |
| 41 | PA, SD (1p, 5p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 176 | 20944.8 | 2 | UniProt (A0A8D0R7A9) Pfam (PF10249) | Sus scrofa (pig) | |
| 42 | QA, TD (1q, 5q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17162.4 | 2 | UniProt (F1SQP4) Pfam (PF05071) | Sus scrofa (pig) | |
| 43 | RA, UD (1r, 5r) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 113 | 12648.6 | 2 | UniProt (A0A8W4F7N8) Pfam (PF07347) | Sus scrofa (pig) | |
| 44 | SA, VD (1s, 5s) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 471 | 48217.8 | 2 | UniProt (A0A4X1TE42) Pfam (PF15880) | Sus scrofa (pig) | |
| 45 | DB, GE, TA, WD (3A, 3N, 6A, 6N) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 480 | 52756.3 | 4 | UniProt (A0A8D0PK14) Pfam (PF00675) Pfam (PF05193) | Sus scrofa (pig) | |
| 46 | EB, HE, UA, XD (3B, 3O, 6B, 6O) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 453 | 48262.4 | 4 | UniProt (F1RPD2) Pfam (PF00675) Pfam (PF05193) | Sus scrofa (pig) | |
| 47 | FB, IE, VA, YD (3C, 3P, 6C, 6P) | Cytochrome b | polymer | 379 | 42840.7 | 4 | UniProt (Q1HBG9) Pfam (PF00033) Pfam (PF00032) | Sus scrofa (pig) | |
| 48 | GB, JE, WA, ZD (3D, 3Q, 6D, 6Q) | Cytochrome c1 | polymer | 326 | 35488.9 | 4 | UniProt (A0A287AZF9) Pfam (PF02167) | Sus scrofa (pig) | |
| 49 | AE, BB, EE, HB, KE... (3E, 3I, 3R, 3V, 6E...) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 274 | 29492.6 | 8 | UniProt (A0A480EHC1) Pfam (PF09165) Pfam (PF02921) Pfam (PF00355) | Sus scrofa (pig) | |
| 50 | BE, IB, LE, YA (3F, 3S, 6F, 6S) | Cytochrome b-c1 complex subunit 7 | polymer | 111 | 13587.5 | 4 | UniProt (A0A286ZPR8) Pfam (PF02271) | Sus scrofa (pig) | |
| 51 | CE, JB, ME, ZA (3G, 3T, 6G, 6T) | Cytochrome b-c1 complex subunit 8 | polymer | 82 | 9784.3 | 4 | UniProt (A0A8D0SHY6) Pfam (PF02939) | Sus scrofa (pig) | |
| 52 | AB, DE, KB, NE (3H, 3U, 6H, 6U) | Cytochrome b-c1 complex subunit 6, mitochondrial | polymer | 91 | 10685.8 | 4 | UniProt (A0A8D1JI21) Pfam (PF02320) | Sus scrofa (pig) | |
| 53 | CB, FE, MB, PE (3J, 3W, 6J, 6W) | Ubiquinol-cytochrome c reductase complex 7.2 kDa protein | polymer | 64 | 7412.5 | 4 | UniProt (Q2EN79) Pfam (PF05365) | Sus scrofa (pig) | |
| 54 | NB, OB, QE, RE (3X, 3Y, 6X, 6Y) | Cytochrome b-c1 complex subunit 10 | polymer | 56 | 6560.7 | 4 | UniProt (F1SDI2) Pfam (PF08997) | Sus scrofa (pig) | |
| 55 | PB, SE (4A, 8A) | Cytochrome c oxidase subunit 1 | polymer | 514 | 57020.7 | 2 | UniProt (O79876) Pfam (PF00115) | Sus scrofa (pig) | Cytochrome c oxidase polypeptide I |
| 56 | QB, TE (4B, 8B) | Cytochrome c oxidase subunit 2 | polymer | 229 | 26288.6 | 2 | UniProt (Q69GF7) Pfam (PF02790) Pfam (PF00116) | Sus scrofa (pig) | |
| 57 | RB, UE (4C, 8C) | Cytochrome c oxidase subunit 3 | polymer | 261 | 29753.4 | 2 | UniProt (Q35916) Pfam (PF00510) | Sus scrofa (pig) | |
| 58 | SB, VE (4D, 8D) | Cytochrome c oxidase subunit 4 | polymer | 169 | 19670.7 | 2 | UniProt (A0A4X1T8J9) Pfam (PF02936) | Sus scrofa (pig) | |
| 59 | TB, WE (4E, 8E) | Cytochrome c oxidase subunit 5A, mitochondrial | polymer | 152 | 16771.2 | 2 | UniProt (F1SJ34) Pfam (PF02284) | Sus scrofa (pig) | |
| 60 | UB, XE (4F, 8F) | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 129 | 13801.8 | 2 | UniProt (Q5S3G4) Pfam (PF01215) | Sus scrofa (pig) | |
| 61 | VB, YE (4G, 8G) | Cytochrome c oxidase subunit 6A2 | polymer | 97 | 10876.4 | 2 | UniProt (A0A287AEB7) Pfam (PF02046) | Sus scrofa (pig) | |
| 62 | WB, ZE (4H, 8H) | Cytochrome c oxidase subunit 6B1 | polymer | 86 | 10204.5 | 2 | UniProt (A1XQT1) Pfam (PF02297) | Sus scrofa (pig) | |
| 63 | AF, XB (4I, 8I) | Cytochrome c oxidase subunit 6C | polymer | 75 | 8617.1 | 2 | UniProt (A0A4X1TXH1) Pfam (PF02937) | Sus scrofa (pig) | |
| 64 | BF, YB (4J, 8J) | Cytochrome c oxidase subunit 7A1, mitochondrial | polymer | 80 | 9028.5 | 2 | UniProt (Q8SPJ9) Pfam (PF02238) | Sus scrofa (pig) | |
| 65 | CF, ZB (4K, 8K) | Cytochrome c oxidase subunit 7B | polymer | 80 | 9169.5 | 2 | UniProt (A0A287BJ57) Pfam (PF05392) | Sus scrofa (pig) | |
| 66 | AC, DF (4L, 8L) | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 63 | 7358.7 | 2 | UniProt (Q1W0Y2) Pfam (PF02935) | Sus scrofa (pig) | |
| 67 | BC, EF (4M, 8M) | Cytochrome c oxidase subunit 8 | polymer | 70 | 7615.9 | 2 | UniProt (A1XQT4) Pfam (PF02285) | Sus scrofa (pig) | |
| 68 | CC, FF (4N, 8N) | Cytochrome c oxidase subunit NDUFA4 | polymer | 82 | 9322.8 | 2 | UniProt (A1XQS3) Pfam (PF06522) | Sus scrofa (pig) | |
| 69 | AG, AK, BG, CJ, DG... (1L, 5d, 1M, 5J, 5L...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 32 | Chemie (3PE) | |||
| 70 | AJ, HF, LF, MF, NF... (5I, 1B, 1F, 1G, 5B...) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 12 | Chemie (SF4) | |||
| 71 | AH, BJ, CG, DK, GK... (1m, 5I, 1M, 5h, 5m...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 20 | Chemie (PC1) | |||
| 72 | HH, JF, LH, MK, OF... (3E, 1E, 3R, 6E, 1G...) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 8 | Chemie (FES) | |||
| 73 | KF, RI (1F, 5F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
| 74 | PF, WI (1G, 5G) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 75 | AL, BK, DH, DL, EJ... (8A, 5d, 1q, 8B, 5L...) | CARDIOLIPIN | non-polymer | 1464.0 | 17 | Chemie (CDL) | |||
| 76 | HG, NJ (1O, 5O) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 77 | IG, OJ, TH, YK (1O, 5O, 4A, 8A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 78 | KG, QJ (1P, 5P) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 79 | GI, LG, NL, RJ (4F, 1R, 8F, 5R) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 80 | BH, HK, MG, SJ (1n, 5n, 1T, 5T) | ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate | non-polymer | 584.7 | 4 | Chemie (EHZ) | |||
| 81 | CK, WG (5h, 1h) | N-ACETYLMETHIONINE | non-polymer | 191.2 | 2 | Chemie (AME) | |||
| 82 | AI, BI, CH, CI, CL... (4C, 1p, 8B, 8C, 4G...) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 28 | Chemie (PGV) | |||
| 83 | EH, FH, IH, JH, JK... (3C, 3P, 6C, 6P) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 8 | Chemie (HEM) | |||
| 84 | GH, KH, LK, PK (3D, 3Q, 6D, 6Q) | HEME C | non-polymer | 618.5 | 4 | Chemie (HEC) | |||
| 85 | QH, RH, VK, WK (4A, 8A) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 86 | SH, XK (4A, 8A) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 87 | UH, ZK (4A, 8A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 88 | EL, WH (8B, 4B) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 89 | BL, XH (8A, 4B) | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) | |||
| 90 | DI, EI, KL, LL (4C, 8C) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 4 | Chemie (PEK) | |||
| 91 | II, PL (4H, 8H) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) |
Sequence modifications
1i, 5i: 1 - 127 (UniProt: A0A4X1UIV8)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 162 |
| Total formula weight | 3792410.7 | |
| Non-Polymers* | Number of molecules | 169 |
| Total formula weight | 113861.2 | |
| All* | Total formula weight | 3906272.0 |
