8UGB
Cryo-EM structure of bovine phosphodiesterase 6 bound to udenafil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | polymer | 859 | 99461.8 | 1 | UniProt (P11541) Pfam (PF01590) Pfam (PF00233) | Bos taurus (cattle) | GMP-PDE alpha,PDE V-B1 |
| 2 | B (B) | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | polymer | 853 | 98449.6 | 1 | UniProt (P23439) Pfam (PF01590) Pfam (PF00233) | Bos taurus (cattle) | GMP-PDE beta |
| 3 | C, D (C, D) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | polymer | 87 | 9684.2 | 2 | UniProt (P04972) Pfam (PF04868) | Bos taurus (cattle) | GMP-PDE gamma |
| 4 | E, I (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) | |||
| 5 | F, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | H, L (A, B) | Udenafil | non-polymer | 516.7 | 2 | Chemie (ZUD) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 217279.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1903.1 | |
| All* | Total formula weight | 219183.0 |
