8UGB
Cryo-EM structure of bovine phosphodiesterase 6 bound to udenafil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | polymer | 859 | 99461.8 | 1 | UniProt (P11541) Pfam (PF01590) Pfam (PF00233) | Bos taurus (cattle) | GMP-PDE alpha,PDE V-B1 |
| 2 | B (B) | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | polymer | 853 | 98449.6 | 1 | UniProt (P23439) Pfam (PF01590) Pfam (PF00233) | Bos taurus (cattle) | GMP-PDE beta |
| 3 | C, D (C, D) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | polymer | 87 | 9684.2 | 2 | UniProt (P04972) Pfam (PF04868) | Bos taurus (cattle) | GMP-PDE gamma |
| 4 | E, I (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) PubChem (136268916) PubChem (136678837) PubChem (136759845) PubChem (137279777) PubChem (164162904) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (137218937) PubChem (137234705) PubChem (138399475) | |||
| 5 | F, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 7 | H, L (A, B) | Udenafil | non-polymer | 516.7 | 2 | Chemie (ZUD) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 217279.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1903.1 | |
| All* | Total formula weight | 219183.0 |
