8UE2
Structure of TREK-1CG*:ML335
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Potassium channel subfamily K member 2 | polymer | 287 | 31577.9 | 2 | UniProt (P97438) Pfam (PF07885) In PDB | Mus musculus (house mouse) | Outward rectifying potassium channel protein TREK-1,TREK-1 K(+) channel subunit,Two pore potassium channel TPKC1 |
2 | A, B | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
3 | A, B | HEXADECANE | non-polymer | 226.4 | 12 | Chemie (R16) | |||
4 | A | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
5 | B, A | N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]benzamide | non-polymer | 373.3 | 2 | Chemie (Q6F) | |||
6 | A, B | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) |
Sequence modifications
A, B: 35 - 321 (UniProt: P97438)
PDB | External Database | Details |
---|---|---|
Arg 84 | Lys 84 | engineered mutation |
Glu 85 | Gln 85 | engineered mutation |
Lys 86 | Thr 86 | engineered mutation |
Leu 88 | Ile 88 | engineered mutation |
Arg 89 | Ala 89 | engineered mutation |
Ala 90 | Gln 90 | engineered mutation |
Pro 92 | Ala 92 | engineered mutation |
Ser 95 | Asn 95 | engineered mutation |
Asp 96 | Ser 96 | engineered mutation |
Gln 97 | Thr 97 | engineered mutation |
Ala 119 | Asn 119 | engineered mutation |
Cys 131 | Ser 131 | engineered mutation |
Ala 300 | Ser 300 | engineered mutation |
Ala 306 | Glu 306 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63155.8 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 4290.3 | |
All* | Total formula weight | 67446.1 |