8UDR
Structure of the P1B7 antibody bound to the Sotorasib-modified KRas G12C peptide presented by the A*03:01 MHC I complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 275 | 31758.0 | 1 | UniProt (P04439) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | GTPase KRas, N-terminally processed | polymer | 10 | 889.1 | 1 | UniProt (P01116) | Homo sapiens | |
| 4 | D (D) | P1B7 Heavy Chain | polymer | 226 | 24103.0 | 1 | Homo sapiens | ||
| 5 | E (E) | P1B7 Light Chain | polymer | 213 | 22580.8 | 1 | Homo sapiens | ||
| 6 | F (D) | AMG 510 (bound form) | non-polymer | 562.6 | 1 | Chemie (MOV) |
Sequence modifications
C: 7 - 16 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Cys 12 | Gly 12 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 91079.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 562.6 | |
| All* | Total formula weight | 91641.7 |
