8UD5

SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	F, D, E, B, A...	Non-structural protein 15	polymer	359	40208.6	6	UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	nsp7
2	G	RNA (35-MER)	polymer	35	10837.1	1		Severe acute respiratory syndrome coronavirus 2
3	H	RNA (35-MER)	polymer	35	11401.0	1		Severe acute respiratory syndrome coronavirus 2

Sequence modifications

F, D, E, B, A, C: 1 - 346 (UniProt: P0DTD1)

PDB	External Database	Details
Met -12	-	initiating methionine
Gly -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Ala 234	His 6686	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	263489.9
All*	Total formula weight	263489.9

*Water molecules are not included.