8UD1
High resolution in-situ structure of complex I in respiratory supercomplex (composite)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13026.5 | 1 | UniProt (O79880) Pfam (PF00507) | Sus scrofa (pig) | NADH dehydrogenase subunit 3 |
| 2 | B (1B) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | polymer | 258 | 28500.2 | 1 | UniProt (A0A4X1VVS8) | Sus scrofa (pig) | |
| 3 | C (1C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 264 | 30241.4 | 1 | UniProt (A0A286ZNN4) Pfam (PF00329) | Sus scrofa (pig) | Complex I-30kD,NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 4 | D (1D) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 466 | 52953.8 | 1 | UniProt (A0A8D1TTB3) | Sus scrofa (pig) | Complex I-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 5 | E (1E) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 249 | 27439.5 | 1 | UniProt (A0A4X1VRV3) | Sus scrofa (pig) | |
| 6 | F (1F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50637.8 | 1 | UniProt (A0A4X1SZP7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Sus scrofa (pig) | |
| 7 | G (1G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79627.4 | 1 | UniProt (A0A287ARY3) Pfam (PF00384) Pfam (PF09326) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) | Sus scrofa (pig) | |
| 8 | H (1H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35619.4 | 1 | UniProt (A0A0U1RS44) Pfam (PF00146) | Sus scrofa (pig) | |
| 9 | I (1I) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 239 | 27135.0 | 1 | UniProt (A0A286ZUN9) Pfam (PF12838) | Sus scrofa (pig) | |
| 10 | J (1J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 1 | UniProt (O79882) Pfam (PF00499) | Sus scrofa (pig) | |
| 11 | K (1K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10855.3 | 1 | UniProt (P56632) Pfam (PF00420) | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 12 | L (1L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68723.5 | 1 | UniProt (Q9TDR1) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Sus scrofa (pig) | NADH dehydrogenase subunit 5 |
| 13 | M (1M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51887.4 | 1 | UniProt (O79881) Pfam (PF01059) Pfam (PF00361) | Sus scrofa (pig) | NADH dehydrogenase subunit 4 |
| 14 | N (1N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39105.5 | 1 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 15 | O (1O) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 357 | 40476.1 | 1 | UniProt (F1SIS9) Pfam (PF01712) | Sus scrofa (pig) | |
| 16 | P (1P) | NADH:ubiquinone oxidoreductase subunit A9 | polymer | 377 | 42606.3 | 1 | UniProt (A0A4X1ULW2) | Sus scrofa (pig) | |
| 17 | Q (1Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 175 | 19746.5 | 1 | UniProt (A0A4X1SN37) Pfam (PF04800) | Sus scrofa (pig) | |
| 18 | R (1R) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 123 | 13349.0 | 1 | UniProt (A0A4X1THU2) | Sus scrofa (pig) | |
| 19 | S (1S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 11099.8 | 1 | UniProt (A0A8D1FN21) | Sus scrofa (pig) | |
| 20 | T, U (1T, 1U) | NADH:ubiquinone oxidoreductase subunit AB1 | polymer | 156 | 17338.2 | 2 | UniProt (A0A8D1KH26) | Sus scrofa (pig) | |
| 21 | V (1V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1 | polymer | 116 | 13321.6 | 1 | UniProt (A0A8D0UWW0) | Sus scrofa (pig) | |
| 22 | W (1W) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 128 | 14953.3 | 1 | UniProt (A0A480VKQ8) | Sus scrofa (pig) | |
| 23 | X (1X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 172 | 20064.1 | 1 | UniProt (A0A8D0K6B5) | Sus scrofa (pig) | |
| 24 | Y (1Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 141 | 14686.9 | 1 | UniProt (I3LGM4) Pfam (PF02466) | Sus scrofa (pig) | |
| 25 | Z (1Z) | NADH:ubiquinone oxidoreductase subunit A13 | polymer | 144 | 16911.6 | 1 | UniProt (A0A8D0K655) | Sus scrofa (pig) | |
| 26 | AA (1a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8034.4 | 1 | UniProt (A0A8D0TJQ4) | Sus scrofa (pig) | |
| 27 | BA (1b) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 84 | 9225.6 | 1 | UniProt (A0A4X1VQ42) | Sus scrofa (pig) | |
| 28 | CA (1c) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 76 | 8664.1 | 1 | UniProt (A0A8D1EYQ2) | Sus scrofa (pig) | |
| 29 | DA (1d) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 122 | 14327.7 | 1 | UniProt (A0A480JRW3) Pfam (PF06374) | Sus scrofa (pig) | |
| 30 | EA (1e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 106 | 12506.6 | 1 | UniProt (A0A4X1VX77) | Sus scrofa (pig) | |
| 31 | FA (1f) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 58 | 7044.3 | 1 | UniProt (A0A4X1SNY5) | Sus scrofa (pig) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 32 | GA (1g) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 154 | 17384.7 | 1 | UniProt (A0A8D1EYI7) | Sus scrofa (pig) | |
| 33 | HA (1h) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 189 | 21587.0 | 1 | UniProt (F1SGC6) Pfam (PF09781) | Sus scrofa (pig) | |
| 34 | IA (1i) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 128 | 15645.2 | 1 | UniProt (A0A4X1UIV8) | Sus scrofa (pig) | |
| 35 | JA (1j) | NADH:ubiquinone oxidoreductase subunit B2 | polymer | 105 | 11939.4 | 1 | UniProt (A0A8D1G9F4) | Sus scrofa (pig) | |
| 36 | KA (1k) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 98 | 11128.5 | 1 | UniProt (A0A4X1VD84) Pfam (PF08122) | Sus scrofa (pig) | |
| 37 | LA (1l) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 186 | 21658.4 | 1 | UniProt (B8Y651) | Sus scrofa (pig) | |
| 38 | MA (1m) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 129 | 15117.4 | 1 | UniProt (A0A4X1T6M0) Pfam (PF07225) | Sus scrofa (pig) | |
| 39 | NA (1n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 179 | 21864.9 | 1 | UniProt (K7GSE5) Pfam (PF05347) | Sus scrofa (pig) | |
| 40 | OA (1o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 137 | 16487.9 | 1 | UniProt (F1SCH1) Pfam (PF05676) | Sus scrofa (pig) | |
| 41 | PA (1p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 176 | 20944.8 | 1 | UniProt (A0A8D0R7A9) | Sus scrofa (pig) | |
| 42 | QA (1q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17162.4 | 1 | UniProt (F1SQP4) Pfam (PF05071) | Sus scrofa (pig) | |
| 43 | RA (1r) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 113 | 12690.6 | 1 | UniProt (A0A8W4F7N8) Pfam (PF07347) | Sus scrofa (pig) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 44 | SA (1s) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 471 | 48217.8 | 1 | UniProt (A0A4X1TE42) | Sus scrofa (pig) | |
| 45 | CB, DB, GB, JC, KC... (1H, 1I, 1d, 1f, 1h...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 14 | Chemie (PC1) PubChem (65146) PubChem (94190) PubChem (10417837) | |||
| 46 | EB, FB, UA, XA, YA... (1I, 1B, 1F, 1G) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 47 | AB, VA (1G, 1E) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 48 | WA (1F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (23585816) PubChem (8965) PubChem (51435500) PubChem (51435503) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (15559251) | |||
| 49 | BB (1G) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 50 | CC, DC, EC, FC, GC... (1Y, 1b, 1J, 1d, 1L...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 18 | Chemie (3PE) | |||
| 51 | BC, IC, LC, MB, SB... (1X, 1d, 1h, 1L, 1N...) | CARDIOLIPIN | non-polymer | 1464.0 | 6 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 52 | UB (1O) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 53 | VB (1O) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 54 | YB (1P) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 55 | ZB (1R) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 56 | AC, SC (1W, 1n) | ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate | non-polymer | 584.7 | 2 | Chemie (EHZ) PubChem (71777704) PubChem (137349255) PubChem (163183360) | |||
| 57 | OC (1l) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) PubChem (11005) | |||
| 58 | AD, AE, BD, BE, CD... (1E, 1e, 1F, 1f, 1G...) | water | water | 18.0 | 4265 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 1088297.2 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 39024.5 | |
| All* | Total formula weight | 1127321.7 |
