8UD1
High resolution in-situ structure of complex I in respiratory supercomplex (composite)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13026.5 | 1 | UniProt (O79880) Pfam (PF00507) | Sus scrofa (pig) | NADH dehydrogenase subunit 3 |
| 2 | B (1B) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | polymer | 258 | 28500.2 | 1 | UniProt (A0A4X1VVS8) Pfam (PF01058) | Sus scrofa (pig) | |
| 3 | C (1C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 264 | 30241.4 | 1 | UniProt (A0A286ZNN4) Pfam (PF00329) | Sus scrofa (pig) | Complex I-30kD,NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 4 | D (1D) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 466 | 52953.8 | 1 | UniProt (A0A8D1TTB3) Pfam (PF00346) | Sus scrofa (pig) | Complex I-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 5 | E (1E) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 249 | 27439.5 | 1 | UniProt (A0A4X1VRV3) Pfam (PF01257) | Sus scrofa (pig) | |
| 6 | F (1F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50637.8 | 1 | UniProt (A0A4X1SZP7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Sus scrofa (pig) | |
| 7 | G (1G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79627.4 | 1 | UniProt (A0A287ARY3) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) Pfam (PF13510) | Sus scrofa (pig) | |
| 8 | H (1H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35619.4 | 1 | UniProt (A0A0U1RS44) Pfam (PF00146) | Sus scrofa (pig) | |
| 9 | I (1I) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 239 | 27135.0 | 1 | UniProt (A0A286ZUN9) Pfam (PF12838) | Sus scrofa (pig) | |
| 10 | J (1J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 1 | UniProt (O79882) Pfam (PF00499) | Sus scrofa (pig) | |
| 11 | K (1K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10855.3 | 1 | UniProt (P56632) Pfam (PF00420) | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 12 | L (1L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68723.5 | 1 | UniProt (Q9TDR1) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Sus scrofa (pig) | NADH dehydrogenase subunit 5 |
| 13 | M (1M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51887.4 | 1 | UniProt (O79881) Pfam (PF01059) Pfam (PF00361) | Sus scrofa (pig) | NADH dehydrogenase subunit 4 |
| 14 | N (1N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39105.5 | 1 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 15 | O (1O) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 357 | 40476.1 | 1 | UniProt (F1SIS9) Pfam (PF01712) | Sus scrofa (pig) | |
| 16 | P (1P) | NADH:ubiquinone oxidoreductase subunit A9 | polymer | 377 | 42606.3 | 1 | UniProt (A0A4X1ULW2) Pfam (PF01370) | Sus scrofa (pig) | |
| 17 | Q (1Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 175 | 19746.5 | 1 | UniProt (A0A4X1SN37) Pfam (PF04800) | Sus scrofa (pig) | |
| 18 | R (1R) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 123 | 13349.0 | 1 | UniProt (A0A4X1THU2) Pfam (PF10276) | Sus scrofa (pig) | |
| 19 | S (1S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 11099.8 | 1 | UniProt (A0A8D1FN21) Pfam (PF05047) | Sus scrofa (pig) | |
| 20 | T, U (1T, 1U) | NADH:ubiquinone oxidoreductase subunit AB1 | polymer | 156 | 17338.2 | 2 | UniProt (A0A8D1KH26) Pfam (PF00550) | Sus scrofa (pig) | |
| 21 | V (1V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1 | polymer | 116 | 13321.6 | 1 | UniProt (A0A8D0UWW0) Pfam (PF04716) | Sus scrofa (pig) | |
| 22 | W (1W) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 128 | 14953.3 | 1 | UniProt (A0A480VKQ8) Pfam (PF05347) | Sus scrofa (pig) | |
| 23 | X (1X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 172 | 20064.1 | 1 | UniProt (A0A8D0K6B5) Pfam (PF06747) | Sus scrofa (pig) | |
| 24 | Y (1Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 141 | 14686.9 | 1 | UniProt (I3LGM4) Pfam (PF02466) | Sus scrofa (pig) | |
| 25 | Z (1Z) | NADH:ubiquinone oxidoreductase subunit A13 | polymer | 144 | 16911.6 | 1 | UniProt (A0A8D0K655) Pfam (PF06212) | Sus scrofa (pig) | |
| 26 | AA (1a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8034.4 | 1 | UniProt (A0A8D0TJQ4) Pfam (PF15879) | Sus scrofa (pig) | |
| 27 | BA (1b) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 84 | 9225.6 | 1 | UniProt (A0A4X1VQ42) Pfam (PF14987) | Sus scrofa (pig) | |
| 28 | CA (1c) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 76 | 8664.1 | 1 | UniProt (A0A8D1EYQ2) | Sus scrofa (pig) | |
| 29 | DA (1d) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 122 | 14327.7 | 1 | UniProt (A0A480JRW3) Pfam (PF06374) | Sus scrofa (pig) | |
| 30 | EA (1e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 106 | 12506.6 | 1 | UniProt (A0A4X1VX77) Pfam (PF10200) | Sus scrofa (pig) | |
| 31 | FA (1f) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 58 | 7044.3 | 1 | UniProt (A0A4X1SNY5) Pfam (PF08040) | Sus scrofa (pig) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 32 | GA (1g) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 154 | 17384.7 | 1 | UniProt (A0A8D1EYI7) Pfam (PF10183) | Sus scrofa (pig) | |
| 33 | HA (1h) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 189 | 21587.0 | 1 | UniProt (F1SGC6) Pfam (PF09781) | Sus scrofa (pig) | |
| 34 | IA (1i) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 128 | 15645.2 | 1 | UniProt (A0A4X1UIV8) Pfam (PF09782) | Sus scrofa (pig) | |
| 35 | JA (1j) | NADH:ubiquinone oxidoreductase subunit B2 | polymer | 105 | 11939.4 | 1 | UniProt (A0A8D1G9F4) Pfam (PF14813) | Sus scrofa (pig) | |
| 36 | KA (1k) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 98 | 11128.5 | 1 | UniProt (A0A4X1VD84) Pfam (PF08122) | Sus scrofa (pig) | |
| 37 | LA (1l) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 186 | 21658.4 | 1 | UniProt (B8Y651) Pfam (PF05821) | Sus scrofa (pig) | |
| 38 | MA (1m) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 129 | 15117.4 | 1 | UniProt (A0A4X1T6M0) Pfam (PF07225) | Sus scrofa (pig) | |
| 39 | NA (1n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 179 | 21864.9 | 1 | UniProt (K7GSE5) Pfam (PF05347) | Sus scrofa (pig) | |
| 40 | OA (1o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 137 | 16487.9 | 1 | UniProt (F1SCH1) Pfam (PF05676) | Sus scrofa (pig) | |
| 41 | PA (1p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 176 | 20944.8 | 1 | UniProt (A0A8D0R7A9) Pfam (PF10249) | Sus scrofa (pig) | |
| 42 | QA (1q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17162.4 | 1 | UniProt (F1SQP4) Pfam (PF05071) | Sus scrofa (pig) | |
| 43 | RA (1r) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 113 | 12690.6 | 1 | UniProt (A0A8W4F7N8) Pfam (PF07347) | Sus scrofa (pig) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 44 | SA (1s) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 471 | 48217.8 | 1 | UniProt (A0A4X1TE42) Pfam (PF15880) | Sus scrofa (pig) | |
| 45 | CB, DB, GB, JC, KC... (1H, 1I, 1d, 1f, 1h...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 14 | Chemie (PC1) | |||
| 46 | EB, FB, UA, XA, YA... (1I, 1B, 1F, 1G) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 47 | AB, VA (1G, 1E) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 48 | WA (1F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 49 | BB (1G) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 50 | CC, DC, EC, FC, GC... (1Y, 1b, 1J, 1d, 1L...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 18 | Chemie (3PE) | |||
| 51 | BC, IC, LC, MB, SB... (1X, 1d, 1h, 1L, 1N...) | CARDIOLIPIN | non-polymer | 1464.0 | 6 | Chemie (CDL) | |||
| 52 | UB (1O) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 53 | VB (1O) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 54 | YB (1P) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 55 | ZB (1R) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 56 | AC, SC (1W, 1n) | ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate | non-polymer | 584.7 | 2 | Chemie (EHZ) | |||
| 57 | OC (1l) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 58 | AD, AE, BD, BE, CD... (1E, 1e, 1F, 1f, 1G...) | water | water | 18.0 | 4265 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 1088297.2 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 39024.5 | |
| All* | Total formula weight | 1127321.7 |
