8UCB
IRAK4 in complex with compound 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34657.9 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | E, F, G, H (A, B, C, D) | 6-(difluoromethyl)-N-[(4R)-7-ethoxy-2-{[(3R)-oxolan-3-yl]methyl}imidazo[1,2-a]pyridin-6-yl]pyridine-2-carboxamide | non-polymer | 416.4 | 4 | Chemie (X1T) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 547 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138631.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1665.7 | |
| All* | Total formula weight | 140297.4 |
