8U9J

The crystal structure of iron-bound human ADO C18S C239S variant at 2.02 Angstrom

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	2-aminoethanethiol dioxygenase	polymer	274	30108.1	2	UniProt (Q96SZ5) Pfam (PF07847) In PDB	Homo sapiens (human)	Cysteamine dioxygenase
2	A, B	FE (III) ION	non-polymer		55.8	2	Chemie (FE)
3	A, B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	281	Chemie (HOH)

Sequence modifications

A, B: 2 - 270 (UniProt: Q96SZ5)

PDB	External Database	Details
Gly -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Ser 1	-	expression tag
Ser 18	Cys 18	engineered mutation
Ser 239	Cys 239	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60216.2
Non-Polymers*	Number of molecules	8
	Total formula weight	672.2
All*	Total formula weight	60888.4

*Water molecules are not included.